TyG Index Calculator
Triglyceride-Glucose Index — a validated surrogate for insulin resistance when fasting insulin isn't on your lab panel. The marker most standard checkups miss.
Your fasting labs
Both values must be from a fasting blood sample
Medications that may affect your result
Statins (atorvastatin, rosuvastatin) lower triglycerides, which directly reduces the TyG index. Your result may underestimate metabolic risk if you are on a statin.
Fibrates (fenofibrate, gemfibrozil) significantly lower triglycerides. Same consideration as statins — the TyG index may not fully reflect underlying insulin resistance.
Corticosteroids (prednisone, dexamethasone) raise both triglycerides and blood glucose, which can inflate the TyG index beyond what your baseline metabolic state would produce.
Your baseline may differ from the general population. Discuss with your healthcare provider.
About this tool
Formula
TyG Index = ln(Triglycerides [mg/dL] × Glucose [mg/dL] / 2). Values in mmol/L are converted before calculation: TG × 88.57, Glucose × 18.018.
Why TyG
Most standard lab panels include triglycerides and glucose but not fasting insulin. When fasting insulin is unavailable, the TyG Index provides a validated surrogate measure of insulin resistance — the condition HOMA-IR directly measures. If you have fasting insulin available, use the HOMA-IR Calculator instead for a more precise assessment.
Thresholds
Lower Risk: < 8.0 / Moderate Risk: 8.0–8.8 / Higher Risk: > 8.8. These ranges are derived from multiple published studies correlating TyG with HOMA-IR and metabolic syndrome prevalence.
Limitations
TyG is a surrogate marker — less precise than HOMA-IR when fasting insulin is available. Triglycerides are highly sensitive to recent meals — values must be from a fasting sample. Individual variation is significant. A single measurement should not be interpreted in isolation.
Sources
Simental-Mendia LE et al., The product of fasting glucose and triglycerides as surrogate for identifying insulin resistance, European Journal of Internal Medicine, 2008. Guerrero-Romero F et al., The product of triglycerides and glucose as a simple measure of insulin sensitivity, Journal of Clinical Endocrinology & Metabolism, 2010.
Educational tool only. Not for diagnostic purposes. Consult a healthcare provider for medical decisions.